Tracey Database


Introduction to Tracey database:
This database is a collection of sequences from different protein families, including SNARE, AAA and Rab, classified by HMM profiles.



A detailed description of the different protein families classification can be found in:


SNARE:

Klöpper, T. H., Kienle, C. N., and Fasshauer, D.
An elaborate classification of SNARE proteins sheds light on the conservation of the eukaryotic endomembrane system
Molecular Biology of the Cell, Vol. 18, 3463–3471, September 2007 ( PubMed / PDF)

Klöpper, T. H., Kienle, C. N., and Fasshauer, D.
SNAREing the basis of multicellularity: Consequences of protein family expansion during evolution
Molecular Biology and Evolution 2008; doi: 10.1093/molbev/msn151 ( PubMed / PDF)

Kienle, N., Klöpper, T. H., and Fasshauer, D.
Phylogeny of the SNARE vesicle fusion machinery yields insights into the conservation of the secretory pathway in fungi
BMC Evolutionary Biology 2009, 9:19 ( PubMed / PDF)

Kienle, N., Klöpper, T. H., and Fasshauer, D.
Differences in the SNARE evolution of fungi and metazoa
Biochemical Society Transactions (2009) Volume 37, part 4 ( PubMed)


Rab:

Klöpper, T. H., Kienle, N., Fasshauer, D., and Munro S.
Untangling the evolution of Rab G proteins: implications of a comprehensive genomic analysis
BMC Biology 2012, 10:71 ( PubMed / PDF)


AAA:

Kienle, N., Klöpper, T. H., and Fasshauer, D.
Shedding light on the expansion and diversification of the Cdc48 protein family during the rise of the eukaryotic cell
BMC Evolutionary Biology 2016, 16:215 ( PubMed / PDF)



Supplemental Information
Any supplemental information of publications can be downloaded from the Supplemental Data section of the above cited publication.
To view the Nexus files in the Supplemental Data section you may use SplitsTree
SNARE conformation SNARE overview SNARE classification Rab classification TRACEY phylogenetic tree